No.7 System design of alternative methods for animal experiments using HSPiP Part 2

2023.3.15

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概要:

Continuing from Part 1, I explained how to predict the Draize Score quantitatively. In the usual quantitative analysis, no correlation was found between the Draize Score and the HSP distance. Using the Double Sphere option of HSPiP, I searched for two different Hansen’s Spheres. I found a high correlation when I considered that the chemical permeates whichever has the shorter HSP distance.